Instruments and Services
The Microscopy and Advanced Bioimaging CoRE is a shared resource facility providing access to widefield, laser scanning confocal, spinning disk confocal, multi-photon, light-sheet, and super-resolution microscopes, along with transmission electron microscopes. The facility also houses high-end image processing workstations for image analysis and quantification, providing access to several commercial software programs. More details about the microscope can be found below.
Instruments
Zeiss Axio Imager.Z2 (2x) with motorized XYZ movement
Leica DMi8 for live-cell microscopy
Olympus MVX10 macroscope
Zeiss Axioplan 2ie for polarized light microscopy
Olympus IX71 for simple screening
Super-resolution: Leica TCS SP8 with STED 3x and White Light Laser
Super-resolution: Zeiss LSM 880 Airyscan with 32-linear spectral GaAsP array + 2 PMTs and the Airyscan detector
Super-resolution: Zeiss LSM 980 Airyscan with 32-linear spectral GaAsP array + 2 PMTs + 2 NIR GaAsP detectors and the Airyscan detector
Leica Stellaris 8 with White Light Laser and 4 spectral Power HyD detectors
Leica TCS SP8 with spectral detector
Zeiss LSM 780 with 34-channel spectral detector
Yokogawa Spinning Disk, built on Zeiss Axio Observer.Z1
Olympus FVMPE-RS-with Dual Line Insight X3 laser
Olympus FV1000 with Coherent Chameleon Vision II laser
LaVision Biotec UltraMicroscope II (zoom and infinity optics available)
ThermoFisher CX7 LZR
Transmission Electron Microscope
Hitachi 7500
Hitachi 7700
Light Microscopy Applications
Whole organ/organism live/fixed imaging
Whole organ/organism fluorescence imaging
Super-resolution confocal imaging
Spectral unmixing for multiplexed samples
High-resolution widefield with deconvolution processing available
Fast, high-resolution live-cell imaging with Yokogawa Spinning Disk
FLIM, FCS and FRET
High-content imaging
Optogenetics and electrophysiology
Intra-vital imaging