As a student in our Development, Regeneration and Stem Cells (DRS) Graduate Training Program, you will devote a significant portion of your time to research. Explore our laboratories and learn about our investigators.
| Lab Name | Description |
|---|---|
| Bieker Laboratory | Red blood cell differentiation |
| Blenkinsop Laboratory | Investigating retina disease and regeneration |
| Dubois Laboratory | Investigating human heart development and disease, using pluripotent stem cells and mouse embryo |
| Ezhkova Laboratory | Elucidating the molecular mechanisms that control epidermal stem cells during development and into adulthood with a specific interest in the role of chromatin regulators in these processes |
| Ghaffari Laboratory | Investigating mechanisms that regulate blood stem and progenitor cell formation implicated in the pathophysiology of human blood disorders. We have been focused on the FOXO family of transcription factors, which are key in stress resistance and implicated in enhancing human longevity (FOXO3). |
| Krauss Laboratory | Studying pattern formation and cell differentiation during development and regeneration, how these processes are regulated by cell adhesion and signal transduction, and how defects in them contribute to birth defects and diseases. We apply a multidisciplinary approach that includes mouse models and in vitro systems. |
| Marlow Lab | Studying the zebrafish system, which allows us to use embryological, biochemical, and modern genetic approaches and genome-editing techniques such as CRISPR/Cas9 to access maternally controlled processes during vertebrate animal development. We are using this powerful genetic system to unravel the mechanisms that regulate cell polarization and mRNA transport ─ fundamental processes for germ line stem cell development, fertility, and nervous system function. |
| Mlodzik Laboratory | Studying the regulation and signal outcomes of the Wnt and Notch-pathways in neuronal specification and patterning. A main focus is the regulation of planar cell polarity on these contacts during organogenesis and disease |
| Rendl Laboratory | Studying the function of stem cell niches. A major focus is to uncover how specialized Dermal Papilla (DP) cells act as instructive niche for hair follicle stem cells during embryonic hair follicle formation and adult hair growth and regeneration. |
| Sidi Laboratory | Using genetic and chemical-genetic approaches in live zebrafish embryos and cultured human cancer cells to delineate novel targets for personalized cancer treatments |
| Sokol Laboratory | Studying growth factor signaling and cell polarity in early embryos and progenitor cells. We use Xenopus early embryos to gain insights into vertebrate neural tube closure and associated molecular and physical signaling processes |
| Soriano Laboratory | Studying how biological specificity is acquired upon engagement of PDGF and FGF signaling, focusing on multipotent neural crest cells and craniofacial biology. We also study FGF signaling in the early embryo that governs the establishment of stem cell fates. |
| Zaidi Laboratory Laboratory | Using mouse genetic and genomic approaches to study the mechanisms of skeletal fragility and osteoporosis, and to identify new drug targets. We also study molecular mechanisms underlying genotype-phenotype discordance in rare monogenic disorders such as Gaucher disease. A new focus is on using genomic connectivity mapping to repurpose bisphosphonates for new uses in EGFR-positive cancers. |
| Zwaka Laboratory | Investigating ways to direct pluripotent stem cells to replace human cells affected by injury or disease. Among other things we focus on the mechanisms that maintain pluripotency and are developing an ex vivo model of the human central nervous system to study Parkinson's disease. |